AIM2 Recombinant Protein
Product Sizes
10ug
£268.00
OPCD01224-10UG
50ug
£511.00
OPCD01224-50UG
200ug
£918.00
OPCD01224-200UG
About this Product
- SKU:
- OPCD01224
- Additional Names:
- Absent in melanoma 2;interferon-inducible protein AIM2;PYHIN4.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent; caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
- Gene Details:
- absent in melanoma 2
- Molecular Weight:
- 44kDa
- Protein Details:
- Interferon-inducible protein AIM2
- Purity:
- > 97%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
