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Proteins and Peptides

ADRBK1 Recombinant Protein

Product Sizes
10ug
£261.00
OPCD01153-10UG
50ug
£500.00
OPCD01153-50UG
200ug
£901.00
OPCD01153-200UG
About this Product
SKU:
OPCD01153
Additional Names:
ADRBK1;adrenergic beta receptor kinase 1;BARK1;beta-adrenergic receptor kinase 1;beta-ARK-1;BETA-ARK1;G-protein coupled receptor kinase 2.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors; probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (PubMed:19306925; PubMed:19715378). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by faciltating the trafficking of SMO into the cilium and the stimulation of SMO activity (By similarity).
Gene Details:
G protein-coupled receptor kinase 2
Host:
E. coli
Molecular Weight:
58.28kDa
Protein Details:
Beta-adrenergic receptor kinase 1
Purity:
>95%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins