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Proteins and Peptides

ADAMTS5 Recombinant Protein

Product Sizes
10ug
£261.00
OPCD01109-10UG
50ug
£500.00
OPCD01109-50UG
200ug
£901.00
OPCD01109-200UG
About this Product
SKU:
OPCD01109
Additional Names:
a disintegrin and metalloproteinase with thrombospondin motifs 11;A disintegrin and metalloproteinase with thrombospondin motifs 5;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; 5 (aggrecanase-2);ADAM-TS 11;ADAM-TS 5;ADAMTS11;ADAMTS-11;ADAMTS-5;ADAM-TS5;ADMP-2;aggrecanase-2.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Metalloproteinase that plays an important role in connective tissue organization; development; inflammation; arthritis; and cell migration. ADAMTS5 is an extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including aggrecan; versican; brevican and neurocan (PubMed:16133547; PubMed:18992360). Cleavage within the hyalectans occurs at Glu-Xaa recognition motifs. Plays a role in embryonic development; including limb and cardiac morphogenesis; and skeletal muscle development through its versican remodeling properties. Participates in development of brown adipose tissue and browning of white adipose tissue. Plays an important role for T-lymphocyte migration from draining lymph nodes following viral infection.
Gene Details:
ADAM metallopeptidase with thrombospondin type 1 motif 5
Host:
E. coli
Molecular Weight:
19kDa
Protein Details:
A disintegrin and metalloproteinase with thrombospondin motifs 5
Purity:
> 95%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins