ADAM17 Recombinant Protein
Product Sizes
10ug
£279.00
OPCD01082-10UG
50ug
£543.00
OPCD01082-50UG
200ug
£994.00
OPCD01082-200UG
About this Product
- SKU:
- OPCD01082
- Additional Names:
- a disintegrin and metallopeptidase domain 17;a disintegrin and metalloprotease domain 17;a disintegrin and metalloproteinase domain 17 (tumor necrosis factor; alpha; converting enzyme);ADAM 17;disintegrin and metalloproteinase domain-containing protein 17;TACE;TNF-alpha convertase;TNF-alpha-converting enzyme.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins; including p75 TNF-receptor; interleukin 1 receptor type II; p55 TNF-receptor; transforming growth factor-alpha; L-selectin; growth hormone receptor; MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch; generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2 (By similarity).
- Gene Details:
- ADAM metallopeptidase domain 17
- Host:
- E. coli
- Molecular Weight:
- 30kDa
- Protein Details:
- Disintegrin and metalloproteinase domain-containing protein 17
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
