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Proteins and Peptides

ADAM15 Recombinant Protein

Product Sizes
10ug
£268.00
OPCD01081-10UG
50ug
£522.00
OPCD01081-50UG
200ug
£940.00
OPCD01081-200UG
About this Product
SKU:
OPCD01081
Additional Names:
a disintegrin and metalloproteinase domain 15 (metargidin);disintegrin and metalloproteinase domain-containing protein 15;MDC15;MDC-15;metalloprotease RGD disintegrin protein;metalloproteinase-like; disintegrin-like; and cysteine-rich protein 15;Metargidin.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed; during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
Gene Details:
ADAM metallopeptidase domain 15
Host:
E. coli
Molecular Weight:
21kDa
Protein Details:
Disintegrin and metalloproteinase domain-containing protein 15
Purity:
> 95%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins