ABCA4 Recombinant Protein
Product Sizes
10ug
£268.00
OPCD01006-10UG
50ug
£511.00
OPCD01006-50UG
200ug
£918.00
OPCD01006-200UG
About this Product
- SKU:
- OPCD01006
- Additional Names:
- ABC10;ABCR;ARMD2;ATP binding cassette transporter;ATP-binding cassette sub-family A member 4;ATP-binding cassette transporter; retinal-specific;ATP-binding cassette; sub-family A (ABC1); member 4;ATP-binding transporter; retina-specific;CORD3;FFM;photoreceptor rim protein;retinal-specific ATP-binding cassette transporter;retinal-specific phospholipid-transporting ATPase ABCA4;retina-specific ABC transporter;RIM ABC transporter;RIM protein;RMP;RP19;stargardt disease protein;STGD;STGD1.
- Conjugate:
- Unconjugated
- Concentration:
- 150 ug/mL (prior to lyoph)
- Extra Details:
- In the visual cycle; acts as an inward-directed retinoid flipase; retinoid substrates imported by ABCA4 from the extracellular or intradiscal (rod) membrane surfaces to the cytoplasmic membrane surface are all-trans-retinaldehyde (ATR) and N-retinyl-phosphatidyl-ethanolamine (NR-PE). Once transported to the cytoplasmic surface; ATR is reduced to vitamin A by trans-retinol dehydrogenase (tRDH) and then transferred to the retinal pigment epithelium (RPE) where it is converted to 11-cis-retinal. May play a role in photoresponse; removing ATR/NR-PE from the extracellular photoreceptor surfaces during bleach recovery.
- Gene Details:
- ATP binding cassette subfamily A member 4
- Host:
- E. coli
- Molecular Weight:
- 41kDa
- Protein Details:
- Retinal-specific ATP-binding cassette transporter
- Purity:
- >90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
