A2M Recombinant Protein
Product Sizes
10ug
£268.00
OPCD00981-10UG
50ug
£511.00
OPCD00981-50UG
200ug
£918.00
OPCD00981-200UG
About this Product
- SKU:
- OPCD00981
- Additional Names:
- A2m1;A2maa;A2MAC1;A2mb;alpha-2-M;alpha-2-macroglobulin;alpha-2-macroglobulin-P;Mam.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch; called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region; a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
- Gene Details:
- alpha-2-macroglobulin|alpha-2-macroglobulin-like
- Host:
- E. coli
- Molecular Weight:
- 27kDa
- Protein Details:
- Alpha-2-macroglobulin
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
