ACD Recombinant Protein
Product Sizes
10ug
£268.00
OPCD00925-10UG
50ug
£511.00
OPCD00925-50UG
200ug
£918.00
OPCD00925-200UG
About this Product
- SKU:
- OPCD00925
- Additional Names:
- adrenocortical dysplasia homolog;adrenocortical dysplasia protein homolog.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity; telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
- Gene Details:
- ACD; shelterin complex subunit and telomerase recruitment factor
- Host:
- E. coli
- Molecular Weight:
- 22kDa
- Protein Details:
- Adrenocortical dysplasia protein homolog
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
