DNMT3B Recombinant Protein
Product Sizes
10ug
£268.00
OPCD00858-10UG
50ug
£511.00
OPCD00858-50UG
200ug
£918.00
OPCD00858-200UG
About this Product
- SKU:
- OPCD00858
- Additional Names:
- DNA (cytosine-5)-methyltransferase 3B;DNA methyltransferase MmuIIIB;DNA MTase MmuIIIB;MmuIIIB.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing. In association with DNMT1 and via the recruitment of CTCFL/BORIS; involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Function as transcriptional corepressor by associating with ZHX1 (By similarity). Required for DUX4 silencing in somatic cells (By similarity).
- Gene Details:
- DNA methyltransferase 3B
- Host:
- E. coli
- Molecular Weight:
- 28kDa
- Protein Details:
- DNA (cytosine-5)-methyltransferase 3B
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
