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Proteins and Peptides

DNAJC2 Recombinant Protein

Product Sizes
10ug
£240.00
OPCD00842-10UG
50ug
£452.00
OPCD00842-50UG
200ug
£799.00
OPCD00842-200UG
About this Product
SKU:
OPCD00842
Additional Names:
DnaJ (Hsp40) homolog; subfamily C; member 2;dnaJ homolog subfamily C member 2;M-phase phosphoprotein 11;MPHOSPH11;MPP11;ZRF1;ZUO1;zuotin-related factor 1.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic; acts as a molecular chaperone: component of the ribosome-associated complex (RAC); a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex; stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear; mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub); and promotes the displacement of the polycomb PRC1 complex from chromatin; thereby facilitating transcription activation. Specifically binds DNA sequence 5'-GTCAAGC-3'.
Gene Details:
DnaJ heat shock protein family (Hsp40) member C2
Host:
E. coli
Molecular Weight:
27kDa
Protein Details:
DnaJ homolog subfamily C member 2
Purity:
> 90%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins