HIPK1 Recombinant Protein
Product Sizes
10ug
£261.00
OPCD00703-10UG
50ug
£500.00
OPCD00703-50UG
200ug
£901.00
OPCD00703-200UG
About this Product
- SKU:
- OPCD00703
- Additional Names:
- homeodomain interacting protein kinase 1-like protein;homeodomain-interacting protein kinase 1;Myak;Nbak2;nuclear body associated kinase 2b;nuclear body-associated kinase 2.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress; and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli; thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size; lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.
- Gene Details:
- homeodomain interacting protein kinase 1
- Host:
- E. coli
- Molecular Weight:
- 36kDa
- Protein Details:
- Homeodomain-interacting protein kinase 1
- Purity:
- > 95%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
