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Proteins and Peptides

WTAP Recombinant Protein

Product Sizes
10ug
£225.00
OPCD00548-10UG
50ug
£402.00
OPCD00548-50UG
200ug
£701.00
OPCD00548-200UG
About this Product
SKU:
OPCD00548
Additional Names:
female-lethal(2)D homolog;hFL(2)D;Mum2;PNAS-132;pre-mRNA-splicing regulator WTAP;putative pre-mRNA splicing regulator female-lethal(2D);Wilms tumor 1 associated protein;wilms tumor 1-associating protein;Wilms' tumour 1-associating protein;WT1-associated protein.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
Associated component of the WMM complex; a complex that mediates N6-methyladenosine (m6A) methylation of RNAs; a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:29507755). Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715; PubMed:24407421; PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2; which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).
Gene Details:
WT1 associated protein
Host:
E. coli
Molecular Weight:
21kDa
Protein Details:
Pre-mRNA-splicing regulator WTAP
Purity:
> 95%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins