TOPBP1 Recombinant Protein
Product Sizes
10ug
£246.00
OPCD00470-10UG
50ug
£457.00
OPCD00470-50UG
200ug
£814.00
OPCD00470-200UG
About this Product
- SKU:
- OPCD00470
- Additional Names:
- DNA topoisomerase 2-binding protein 1;DNA topoisomerase II-beta-binding protein 1;DNA topoisomerase II-binding protein 1;Dpb11;TOP2BP1;topoisomerase (DNA) II binding protein 1.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR (PubMed:16530042).
- Gene Details:
- DNA topoisomerase II binding protein 1
- Host:
- E. coli
- Molecular Weight:
- 32kDa
- Protein Details:
- DNA topoisomerase 2-binding protein 1
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
