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Proteins and Peptides

ERI1 Recombinant Protein

Product Sizes
10ug
£235.00
OPCD00383-10UG
50ug
£435.00
OPCD00383-50UG
200ug
£766.00
OPCD00383-200UG
About this Product
SKU:
OPCD00383
Additional Names:
3' exoribonuclease;3'-5' exonuclease ERI1;3'-5' exoribonuclease 1;3'HEXO;enhanced RNAi three prime mRNA exonuclease homolog 1;Eri-1 homolog;HEXO;histone mRNA 3' end-specific exonuclease;histone mRNA 3'-end-specific exoribonuclease;histone mRNA 3'-exonuclease 1;Protein 3'hExo;THEX1;three prime histone mRNA exonuclease 1;three prime mRNA exonuclease 1.
Conjugate:
Unconjugated
Concentration:
200 ug/mL (prior to lyoph)
Extra Details:
RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them; suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro; suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Gene Details:
exoribonuclease 1
Host:
E. coli
Molecular Weight:
48kDa
Protein Details:
3'-5' exoribonuclease 1
Purity:
> 90%
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
2Â[o]C to 8Â[o]C|-80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins