CDKN1B Recombinant Protein
Product Sizes
10ug
£192.00
OPCD00226-10UG
50ug
£333.00
OPCD00226-50UG
200ug
£561.00
OPCD00226-200UG
About this Product
- SKU:
- OPCD00226
- Additional Names:
- AA408329;AI843786;cyclin-dependent kinase inhibitor 1B;cyclin-dependent kinase inhibitor p27;Kip1;p2;p27;p27K;p27Kip1.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Important regulator of cell cycle progression (PubMed:8033213; PubMed:12972555). Inhibits the kinase activity of CDK2 bound to cyclin A; but has little inhibitory activity on CDK2 bound to SPDYA (By similarity). Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes (PubMed:8033213). Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly; stability; and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
- Gene Details:
- cyclin-dependent kinase inhibitor 1B
- Host:
- E. coli
- Molecular Weight:
- 26kDa
- Protein Details:
- Cyclin-dependent kinase inhibitor 1B
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
