TOPBP1 Recombinant Protein
Product Sizes
10ug
£251.00
OPCD00180-10UG
50ug
£478.00
OPCD00180-50UG
200ug
£853.00
OPCD00180-200UG
About this Product
- SKU:
- OPCD00180
- Additional Names:
- 1110031N14Rik;2810429C13Rik;AI256758;D430026L04Rik;DNA topoisomerase 2-binding protein 1;DNA topoisomerase II-beta-binding protein 1;DNA topoisomerase II-binding protein 1;mKIAA0259;topoisomerase (DNA) II beta binding protein.
- Conjugate:
- Unconjugated
- Concentration:
- 200 ug/mL (prior to lyoph)
- Extra Details:
- Required for DNA replication (By similarity). Plays a role in the rescue of stalled replication forks and checkpoint control (PubMed:14718568). Binds double-stranded DNA breaks and nicks as well as single-stranded DNA (By similarity). Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage (By similarity). Induces a large increase in the kinase activity of ATR (By similarity).
- Gene Details:
- topoisomerase (DNA) II binding protein 1
- Host:
- E. coli
- Molecular Weight:
- 32kDa
- Protein Details:
- DNA topoisomerase 2-binding protein 1
- Purity:
- > 90%
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- 2Â[o]C to 8Â[o]C|-80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
