COLEC11 Recombinant Protein
Product Sizes
20ug
£727.00
OPCA05436-20UG
100ug
£1861.00
OPCA05436-100UG
About this Product
- SKU:
- OPCA05436
- Additional Names:
- 3MC2;CL-11;CLK1;CL-K1-I;CL-K1-II;CL-K1-IIa;CL-K1-IIb;Collectin K1;collectin kidney protein 1;collectin sub-family member 11;collectin-11.
- Extra Details:
- Lectin that plays a role in innate immunity; apoptosis and embryogenesis (PubMed:23954398; PubMed:25912189; PubMed:21258343). Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1;2-linked mannose epitope (PubMed:25912189). Primarily recognizes the terminal disaccharide of the glycan (PubMed:25912189). Also recognizes a subset of fucosylated glycans and lipopolysaccharides (PubMed:17179669; PubMed:25912189). Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1 (PubMed:20956340; PubMed:25912189). Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding (Probable). Finally; plays a role in development; probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis (PubMed:21258343; PubMed:28301481).
- Gene Details:
- collectin subfamily member 11
- Molecular Weight:
- 30.1 kDa
- Protein Details:
- Collectin-11
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- Mammalian Cells
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
