ALCAM Recombinant Protein
Product Sizes
20ug
£348.00
OPCA05220-20UG
100ug
£500.00
OPCA05220-100UG
1mg
£1822.00
OPCA05220-1MG
About this Product
- SKU:
- OPCA05220
- Additional Names:
- Activated leukocyte cell adhesion molecule;CD166;CD166 antigen;MEMD.
- Extra Details:
- Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6; as well as homotypic cell-cell contacts (PubMed:7760007; PubMed:15496415; PubMed:15048703; PubMed:16352806; PubMed:23169771; PubMed:24945728). Promotes T-cell activation and proliferation via its interactions with CD6 (PubMed:15048703; PubMed:16352806; PubMed:24945728). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (PubMed:15294938; PubMed:16352806). Mediates homotypic interactions with cells that express ALCAM (PubMed:15496415; PubMed:16352806). Required for normal hematopoietic stem cell engraftment in the bone marrow (PubMed:24740813). Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction (PubMed:23169771). Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions (PubMed:15496415; PubMed:23169771). Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension; axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity).
- Gene Details:
- activated leukocyte cell adhesion molecule
- Molecular Weight:
- 70.8 kDa
- Protein Details:
- CD166 antigen
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
