LAMTOR5 Recombinant Protein
Product Sizes
20ug
£348.00
OPCA04868-20UG
100ug
£500.00
OPCA04868-100UG
1mg
£1822.00
OPCA04868-1MG
About this Product
- SKU:
- OPCA04868
- Additional Names:
- HBV X-interacting protein;HBx-interacting protein;HBXIP;hepatitis B virus x interacting protein;Hepatitis B virus X-interacting protein;hepatitis B virus x-interacting protein (9.6kD);late endosomal/lysosomal adaptor and MAPK and MTOR activator 5;ragulator complex protein LAMTOR5;XIP.
- Extra Details:
- As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1; a signaling complex promoting cell growth in response to growth factors; energy levels; and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase; the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5; interferes with apoptosome assembly; preventing recruitment of pro-caspase-9 to oligomerized APAF1; thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
- Gene Details:
- late endosomal/lysosomal adaptor; MAPK and MTOR activator 5
- Molecular Weight:
- 36.6 kDa
- Protein Details:
- Ragulator complex protein LAMTOR5
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
