LITAF Recombinant Protein
Product Sizes
20ug
£348.00
OPCA04864-20UG
100ug
£500.00
OPCA04864-100UG
1mg
£1822.00
OPCA04864-1MG
About this Product
- SKU:
- OPCA04864
- Additional Names:
- lipopolysaccharide-induced TNF-alpha factor;lipopolysaccharide-induced tumor necrosis factor-alpha factor;LPS-induced TNF-alpha factor;p53-induced gene 7 protein;PIG7;SIMPLE;small integral membrane protein of lysosome/late endosome;TP53I7;tumor protein p53 inducible protein 7.
- Extra Details:
- Plays a role in endosomal protein trafficking and in targeting proteins for lysosomal degradation (PubMed:23166352). Plays a role in targeting endocytosed EGFR and ERGG3 for lysosomal degradation; and thereby helps downregulate downstream signaling cascades (PubMed:23166352). Helps recruit the ESCRT complex components TSG101; HGS and STAM to cytoplasmic membranes (PubMed:23166352). Probably plays a role in regulating protein degradation via its interaction with NEDD4 (PubMed:15776429). May also contribute to the regulation of gene expression in the nucleus (PubMed:10200294; PubMed:15793005). Binds DNA (in vitro) and may play a synergistic role with STAT6 in the nucleus in regulating the expression of various cytokines (PubMed:15793005). May regulate the expression of numerous cytokines; such as TNF; CCL2; CCL5; CXCL1; IL1A and IL10 (PubMed:10200294; PubMed:15793005).
- Gene Details:
- lipopolysaccharide induced TNF factor
- Molecular Weight:
- 44.1 kDa
- Protein Details:
- Lipopolysaccharide-induced tumor necrosis factor-alpha factor
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
