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Proteins and Peptides

PPP1CB Recombinant Protein

Product Sizes
20ug
£348.00
OPCA04580-20UG
100ug
£500.00
OPCA04580-100UG
1mg
£1822.00
OPCA04580-1MG
About this Product
SKU:
OPCA04580
Additional Names:
epididymis secretory sperm binding protein Li 80p;HEL-S-80p;MP;myosin phosphatase;NSLH2;PP1B;PP-1B;PP1beta;PP1c;PPP1beta;PPP1CD;protein phosphatase 1; catalytic subunit; beta isozyme;protein phosphatase 1-beta;protein phosphatase 1-delta;serine/threonine-protein phosphatase PP1-beta catalytic subunit.
Extra Details:
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division; it participates in the regulation of glycogen metabolism; muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex; which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E; determines the circadian period length; through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis; thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
Gene Details:
protein phosphatase 1 catalytic subunit beta
Molecular Weight:
41.1 kDa
Protein Details:
Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Purity:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins