ATG14 Recombinant Protein
Product Sizes
20ug
£348.00
OPCA04508-20UG
100ug
£500.00
OPCA04508-100UG
1mg
£1822.00
OPCA04508-1MG
About this Product
- SKU:
- OPCA04508
- Additional Names:
- ATG14 autophagy related 14 homolog;ATG14L;autophagy-related protein 14-like protein;BARKOR;beclin 1-associated autophagy-related key regulator;Beclin 1-Interacting protein;KIAA0831.
- Extra Details:
- Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052; PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696; PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1; but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity).
- Gene Details:
- autophagy related 14
- Molecular Weight:
- 60.3 kDa
- Protein Details:
- Beclin 1-associated autophagy-related key regulator
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
