PVR Recombinant Protein
Product Sizes
20ug
£348.00
OPCA04392-20UG
100ug
£500.00
OPCA04392-100UG
1mg
£1822.00
OPCA04392-1MG
About this Product
- SKU:
- OPCA04392
- Additional Names:
- CD155;HVED;Necl-5;NECL5;nectin-like protein 5;poliovirus receptor;PVS;TAGE4.
- Extra Details:
- Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site; leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange; and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR; and may trigger fratricide NK cell activation; providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration.
- Gene Details:
- PVR cell adhesion molecule
- Molecular Weight:
- 51.1 kDa
- Protein Details:
- Poliovirus receptor
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
