BECN1 Recombinant Protein
Product Sizes
20ug
£561.00
OPCA04331-20UG
100ug
£793.00
OPCA04331-100UG
1mg
£2446.00
OPCA04331-1MG
About this Product
- SKU:
- OPCA04331
- Additional Names:
- Atg;Atg6;Bcl-2-interacting protein beclin;Beclin-1;Coiled-coil myosin-like BCL2-interacting protein;coiled-coil; myosin-like BCL2-interacting protein.
- Extra Details:
- Plays a central role in autophagy (PubMed:10604474; PubMed:12372286; PubMed:19270693; PubMed:28445460). Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis (PubMed:19270693; PubMed:25275521). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis; probably in the context of PI3KC3-C2 (By similarity). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms (PubMed:25275521). Involved in endocytosis including endosome formation in neuronal cells (PubMed:25275521). May play a role in antiviral host defense (By similarity).
- Gene Details:
- beclin 1; autophagy related
- Molecular Weight:
- 67.6 kDa
- Protein Details:
- Beclin-1
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
