PSMD10 Recombinant Protein
Product Sizes
20ug
£348.00
OPCA03930-20UG
100ug
£500.00
OPCA03930-100UG
1mg
£1822.00
OPCA03930-1MG
About this Product
- SKU:
- OPCA03930
- Additional Names:
- 26S proteasome non-ATPase regulatory subunit 10;26S proteasome regulatory subunit p28;ankyrin repeat protein;dJ889N15.2;gankyrin;hepatocellular carcinoma-associated protein p28-II;p28;p28(GANK);proteasome (prosome; macropain) 26S subunit; non-ATPase; 10.
- Extra Details:
- Acts as a chaperone during the assembly of the 26S proteasome; specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with a PSMD5:PSMC2:PSMC1:PSMD2 module. Independently of the proteasome; regulates EGF-induced AKT activation through inhibition of the RHOA/ROCK/PTEN pathway; leading to prolonged AKT activation. Plays an important role in RAS-induced tumorigenesis.
- Gene Details:
- proteasome 26S subunit; non-ATPase 10
- Molecular Weight:
- 40.4 kDa
- Protein Details:
- 26S proteasome non-ATPase regulatory subunit 10
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
