KITLG Recombinant Protein
Product Sizes
20ug
£348.00
OPCA03892-20UG
100ug
£500.00
OPCA03892-100UG
1mg
£1822.00
OPCA03892-1MG
About this Product
- SKU:
- OPCA03892
- Additional Names:
- c-Kit ligand;DCUA;DFNA69;familial progressive hyperpigmentation 2;FPH2;FPHH;kit ligand;Kitl;KL-1;mast cell growth factor;MGF;SCF;SF;SHEP7;SLF;steel factor;stem cell factor.
- Extra Details:
- Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation; hematopoiesis; stem cell maintenance; gametogenesis; mast cell development; migration and function; and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1; the regulatory subunit of phosphatidylinositol 3-kinase; and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS; RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1; STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1; leading to the production of the cellular signaling molecules diacylglycerol and inositol 1;4;5-trisphosphate. KITLG/SCF acts synergistically with other cytokines; probably interleukins.
- Gene Details:
- KIT ligand
- Molecular Weight:
- 45.5 kDa
- Protein Details:
- Kit ligand
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
