TMPRSS2 Recombinant Protein
Product Sizes
20ug
£463.00
OPCA03288-20UG
100ug
£647.00
OPCA03288-100UG
About this Product
- SKU:
- OPCA03288
- Additional Names:
- epitheliasin;PRSS10;serine protease 10;transmembrane protease serine 2;transmembrane protease; serine 2.
- Extra Details:
- Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms; proteolytic cleavage of ACE2; which might promote viral uptake; and cleavage of coronavirus spike glycoprotein which activates the glycoprotein for cathepsin L-independent host cell entry. Proteolytically cleaves and activates the spike glycoproteins of human coronavirus 229E (HCoV-229E) and human coronavirus EMC (HCoV-EMC) and the fusion glycoproteins F0 of Sendai virus (SeV); human metapneumovirus (HMPV); human parainfluenza 1; 2; 3; 4a and 4b viruses (HPIV). Essential for spread and pathogenesis of influenza A virus (strains H1N1; H3N2 and H7N9); involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.
- Gene Details:
- transmembrane serine protease 2
- Host:
- Yeast
- Molecular Weight:
- 44.8 kDa
- Protein Details:
- Transmembrane protease serine 2
- Purity:
- Greater than 85% as determined by SDS-PAGE.
- Purification:
- Affinity purified using IMAC
- Shipping Conditions:
- Blue Ice
- Source:
- Yeast
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
