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Proteins and Peptides

TLR1 Recombinant Protein

Product Sizes
20ug
£532.00
OPCA03236-20UG
100ug
£923.00
OPCA03236-100UG
1mg
£3573.00
OPCA03236-1MG
About this Product
SKU:
OPCA03236
Additional Names:
CD281;rsc786;TIL;TIL. LPRS5;toll/interleukin-1 receptor-like protein;toll-like receptor 1.
Extra Details:
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed:21078852). Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides; this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Acts via MYD88 and TRAF6; leading to NF-kappa-B activation; cytokine secretion and the inflammatory response.
Gene Details:
toll like receptor 1
Host:
Human
Molecular Weight:
65.2 kDa
Protein Details:
Toll-like receptor 1
Purity:
Greater than 90% as determined by SDS-PAGE.
Purification:
Affinity purified using IMAC
Shipping Conditions:
Blue Ice
Source:
Yeast
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins