MKI67 Recombinant Protein
Product Sizes
20ug
£348.00
OPCA03188-20UG
100ug
£500.00
OPCA03188-100UG
1mg
£1822.00
OPCA03188-1MG
About this Product
- SKU:
- OPCA03188
- Additional Names:
- antigen identified by monoclonal antibody Ki-67;antigen Ki67;KIA;MIB-;MIB-1;Molecular Immunology Borstel antibody 1;PPP1R105;proliferation marker protein Ki-67;proliferation-related Ki-67 antigen;protein phosphatase 1; regulatory subunit 105.
- Extra Details:
- Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome; the perichromosomal layer; and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant; dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA; with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
- Gene Details:
- marker of proliferation Ki-67
- Host:
- Human
- Molecular Weight:
- 75.1 kDa
- Protein Details:
- Proliferation marker protein Ki-67
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
