HLA-DMA Recombinant Protein
Product Sizes
20ug
£348.00
OPCA03187-20UG
100ug
£500.00
OPCA03187-100UG
1mg
£1822.00
OPCA03187-1MG
About this Product
- SKU:
- OPCA03187
- Additional Names:
- class II histocompatibility antigen; M alpha chain;D6S222E;DMA;HLA class II histocompatibility antigen; DM alpha chain;HLADM;MHC class II antigen DMA;really interesting new gene 6 protein;RING6.
- Extra Details:
- HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB); both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes; dendritic cells; macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain and the cytoplasmic tail.
- Gene Details:
- major histocompatibility complex; class II; DM alpha
- Host:
- Human
- Molecular Weight:
- 27.4 kDa
- Protein Details:
- HLA-DMA protein
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
