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Proteins and Peptides

APOBEC3A Recombinant Protein

Product Sizes
20ug
£348.00
OPCA03165-20UG
100ug
£500.00
OPCA03165-100UG
1mg
£1822.00
OPCA03165-1MG
About this Product
SKU:
OPCA03165
Additional Names:
A3A;APOBEC3A;apolipoprotein B mRNA editing enzyme; catalytic polypeptide-like 3A;ARP3;bK150C2.1;DNA dC->dU-editing enzyme APOBEC-3A;phorbolin-1;PHRBN;probable DNA dC->dU-editing enzyme APOBEC-3A.
Extra Details:
DNA deaminase (cytidine deaminase) with restriction activity against viruses; foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Gene Details:
APOBEC3A and APOBEC3B deletion hybrid|apolipoprotein B mRNA editing enzyme catalytic subunit 3A
Molecular Weight:
39 kDa
Protein Details:
DNA dC->dU-editing enzyme APOBEC-3A
Purity:
Greater than 90% as determined by SDS-PAGE.
Purification:
Affinity purified using IMAC
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins