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Proteins and Peptides

KAE1 Recombinant Protein

Product Sizes
20ug
£561.00
OPCA03137-20UG
100ug
£793.00
OPCA03137-100UG
1mg
£2446.00
OPCA03137-1MG
About this Product
SKU:
OPCA03137
Additional Names:
Kinase-associated endopeptidase 1;N6-L-threonylcarbamoyladenine synthase;t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1;tRNA N6-adenosine threonylcarbamoyltransferase;tRNA threonylcarbamoyladenosine biosynthesis protein KAE1;YKR038C.
Extra Details:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction; but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
Gene Details:
tRNA N6-adenosine threonylcarbamoyltransferase
Host:
Yeast
Molecular Weight:
46.7 kDa
Protein Details:
tRNA N6-adenosine threonylcarbamoyltransferase
Purity:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins