SART3 Recombinant Protein
Product Sizes
20ug
£398.00
OPCA03013-20UG
100ug
£571.00
OPCA03013-100UG
1mg
£2191.00
OPCA03013-1MG
About this Product
- SKU:
- OPCA03013
- Additional Names:
- DSAP1;HIV-1 Tat-interacting protein of 110kDa;hSART-3;P100;p110;p110 nuclear RNA-binding protein;p110(nrb);PRP24 homolog;RP11-13G14;SART-3;squamous cell carcinoma antigen recognized by T cells 3;squamous cell carcinoma antigen recognized by T-cells 3;tat-interacting protein of 110 kDa;TIP110.
- Extra Details:
- U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP; an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex; promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination; thereby regulating gene expression and/or DNA repair (PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (By similarity).
- Gene Details:
- spliceosome associated factor 3; U4/U6 recycling protein
- Host:
- Human
- Molecular Weight:
- 35.8 kDa
- Protein Details:
- Squamous cell carcinoma antigen recognized by T-cells 3
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- Yeast
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
