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Proteins and Peptides

IFNT1 Recombinant Protein

Product Sizes
20ug
£615.00
OPCA02877-20UG
100ug
£886.00
OPCA02877-100UG
About this Product
SKU:
OPCA02877
Additional Names:
antiluteolysin;IFNT;IFNT1;IFN-tau1;IFN-tau-1;IFN-tau2;IFN-tau-2;IFN-tau-c2;interferon alpha II;interferon tau-1;interferon tau-2;interferon; trophoblast;interferon-tau1e;interferon-tau3e;TP-1;trophoblast antiluteolytic protein;Trophoblast protein 1;trophoblast protein-1;trophoblast type I interferon;trophoblastin.
Extra Details:
Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors; probably type I interferon receptors; and blocks estrogen receptor expression; preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha; hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This; and a possible direct effect of IFN-tau on prostaglandin synthesis; leads in turn to continued ovarian progesterone secretion; which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary; displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity; high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs; IFN-tau is not virally inducible.
Gene Details:
interferon tau
Host:
Bovine
Molecular Weight:
21.8 kDa
Protein Details:
Interferon tau-1
Purity:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Source:
Yeast
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins