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Proteins and Peptides

ARNT Recombinant Protein

Product Sizes
20ug
£398.00
OPCA02596-20UG
100ug
£550.00
OPCA02596-100UG
About this Product
SKU:
OPCA02596
Additional Names:
aryl hydrocarbon receptor nuclear translocator;bHLHe2;class E basic helix-loop-helix protein 2;dioxin receptor; nuclear translocator;HIF1B;HIF1-beta;HIF-1beta;HIF-1-beta;HIF1BETA;hypoxia-inducible factor 1; beta subunit;Hypoxia-inducible factor 1-beta;TANGO.
Extra Details:
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription (PubMed:28396409).
Gene Details:
aryl hydrocarbon receptor nuclear translocator
Host:
Human
Molecular Weight:
54.8 kDa
Protein Details:
Aryl hydrocarbon receptor nuclear translocator
Purity:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Source:
Yeast
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins