TGS1 Recombinant Protein
Product Sizes
20ug
£348.00
OPCA02418-20UG
100ug
£500.00
OPCA02418-100UG
1mg
£1822.00
OPCA02418-1MG
About this Product
- SKU:
- OPCA02418
- Additional Names:
- cap-specific guanine-N2 methyltransferase;CLL-associated antigen KW-2;hepatocellular carcinoma-associated antigen 137;NCOA6IP;nuclear receptor coactivator 6-interacting protein;PIMT;PIPMT;PRIP-interacting protein with methyltransferase motif;trimethylguanosine synthase.
- Extra Details:
- Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2;2;7-trimethylguanosine (m(2;2;7)G) cap structure. The enzyme is specific for guanine; and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci; their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.
- Gene Details:
- trimethylguanosine synthase 1
- Host:
- Human
- Molecular Weight:
- 31.6 kDa
- Protein Details:
- Trimethylguanosine synthase
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
