DCP2 Recombinant Protein
Product Sizes
20ug
£348.00
OPCA02346-20UG
100ug
£500.00
OPCA02346-100UG
1mg
£1822.00
OPCA02346-1MG
About this Product
- SKU:
- OPCA02346
- Additional Names:
- DCP2 decapping enzyme homolog;hDpc;m7GpppN-mRNA hydrolase;mRNA-decapping enzyme 2;Nucleoside diphosphate-linked moiety X motif 20;nudix (nucleoside diphosphate linked moiety X)-type motif 20;NUDT20.
- Extra Details:
- Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs (PubMed:12417715; PubMed:12218187; PubMed:12923261; PubMed:21070968). Removes the 7-methyl guanine cap structure from mRNA molecules; yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (PubMed:12486012; PubMed:12923261; PubMed:21070968). Necessary for the degradation of mRNAs; both in normal mRNA turnover and in nonsense-mediated mRNA decay (PubMed:14527413). Plays a role in replication-dependent histone mRNA degradation (PubMed:18172165). Has higher activity towards mRNAs that lack a poly(A) tail (PubMed:21070968). Has no activity towards a cap structure lacking an RNA moiety (PubMed:21070968). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts (PubMed:26098573).
- Gene Details:
- decapping mRNA 2
- Host:
- Human
- Molecular Weight:
- 48.4 kDa
- Protein Details:
- m7GpppN-mRNA hydrolase
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Purification:
- Affinity purified using IMAC
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. - Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
