AC1 Recombinant Protein
Product Sizes
20ug
£561.00
OPCA02023-20UG
100ug
£793.00
OPCA02023-100UG
1mg
£2446.00
OPCA02023-1MG
About this Product
- SKU:
- OPCA02023
- Additional Names:
- 40.4 kDa protein;Protein AC1;Protein AL1.
- Extra Details:
- Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5'-TAATATTAC-3' in the intergenic region of the genome present in all geminiviruses; thereby initiating the rolling circle replication (RCR). Following cleavage; binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication; a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome; thereby terminating the replication. Displays origin-specific DNA cleavage; nucleotidyl transferase; ATPase and helicase activities (By similarity).
- Molecular Weight:
- 56.3 kDa
- Protein Details:
- Replication-associated protein
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
