XPC Recombinant Protein
Product Sizes
20ug
£348.00
OPCA01929-20UG
100ug
£500.00
OPCA01929-100UG
1mg
£1822.00
OPCA01929-1MG
About this Product
- SKU:
- OPCA01929
- Additional Names:
- DNA repair protein complementing XP-C cells;mutant xeroderma pigmentosum group C;p125;RAD4;Xeroderma pigmentosum group C-complementing protein;xeroderma pigmentosum; complementation group C;XP3;XPCC.
- Extra Details:
- Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity.
- Gene Details:
- XPC complex subunit; DNA damage recognition and repair factor
- Host:
- Human
- Molecular Weight:
- 31.5 kDa
- Protein Details:
- DNA repair protein complementing XP-C cells
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
