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Proteins and Peptides

POLR3K Recombinant Protein

Product Sizes
20ug
£348.00
OPCA01791-20UG
100ug
£500.00
OPCA01791-100UG
1mg
£1822.00
OPCA01791-1MG
About this Product
SKU:
OPCA01791
Additional Names:
C11;C11-RNP3;DNA-directed RNA polymerase III subunit K;DNA-directed RNA polymerase III subunit RPC10;DNA-directed RNA polymerases III 12.5 kDa polypeptide;HLD21;My010;polymerase (RNA) III (DNA directed) polypeptide K; 12.3 kDa;polymerase (RNA) III subunit K;RNA polymerase III 12.5 kDa subunit;RNA polymerase III subunit C10;RNA polymerase III subunit C11;RNA polymerase III subunit CII;RPC10;RPC11;RPC12.5.
Extra Details:
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs; such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts; such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Gene Details:
RNA polymerase III subunit K
Host:
Human
Molecular Weight:
28.3 kDa
Protein Details:
DNA-directed RNA polymerase III subunit RPC10
Purity:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins