ID2 Recombinant Protein
Product Sizes
20ug
£348.00
OPCA01651-20UG
100ug
£500.00
OPCA01651-100UG
1mg
£1822.00
OPCA01651-1MG
About this Product
- SKU:
- OPCA01651
- Additional Names:
- bHLHb26;cell growth-inhibiting gene 8;class B basic helix-loop-helix protein 26;DNA-binding protein inhibitor ID2;DNA-binding protein inhibitor ID-2;GIG8;helix-loop-helix protein ID2;ID2A;ID2H;inhibitor of differentiation 2;Inhibitor of DNA binding 2;inhibitor of DNA binding 2; dominant negative helix-loop-helix protein;inhibitor of DNA binding 2; HLH protein.
- Extra Details:
- Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes; including cellular growth; senescence; differentiation; apoptosis; angiogenesis; and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component; is involved in modulating the magnitude of photic entrainment and in the output component; contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
- Gene Details:
- inhibitor of DNA binding 2
- Host:
- Human
- Molecular Weight:
- 30.9 kDa
- Protein Details:
- DNA-binding protein inhibitor ID-2
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
