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Proteins and Peptides

DNAJB2 Recombinant Protein

Product Sizes
20ug
£348.00
OPCA01564-20UG
100ug
£500.00
OPCA01564-100UG
1mg
£1822.00
OPCA01564-1MG
About this Product
SKU:
OPCA01564
Additional Names:
CMT2T;DnaJ (Hsp40) homolog; subfamily B; member 2;dnaJ homolog subfamily B member 2;dnaJ protein homolog 1;DSMA5;heat shock 40 kDa protein 3;heat shock protein J1;heat shock protein; neuronal DNAJ-like 1;HSJ1;HSJ-1;HSPF3.
Extra Details:
Functions as a co-chaperone; regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family (PubMed:7957263; PubMed:22219199). In parallel; also contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins (PubMed:15936278; PubMed:21625540). Thereby; may regulate the aggregation and promote the functional recovery of misfolded proteins like HTT; MC4R; PRKN; RHO and SOD1 and be crucial for many biological processes (PubMed:12754272; PubMed:20889486; PubMed:21719532; PubMed:22396390; PubMed:24023695). Isoform 1 which is localized to the endoplasmic reticulum membranes may specifically function in ER-associated protein degradation of misfolded proteins (PubMed:15936278).
Gene Details:
DnaJ heat shock protein family (Hsp40) member B2
Host:
Human
Molecular Weight:
51.4 kDa
Protein Details:
DnaJ homolog subfamily B member 2
Purity:
Greater than 90% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Source:
E.coli
Storage Conditions:
-20Â[o]C or -80Â[o]C
Supplier:
Aviva Systems Biology
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins