ASNA1 Recombinant Protein
Product Sizes
20ug
£348.00
OPCA01472-20UG
100ug
£500.00
OPCA01472-100UG
1mg
£1822.00
OPCA01472-1MG
About this Product
- SKU:
- OPCA01472
- Additional Names:
- arsA arsenite transporter; ATP-binding; homolog 1;ARSA1;ARSA-I;Arsenical pump-driving ATPase;Arsenite-stimulated ATPase;ASNA1;ASNA-I;ATPase GET3;golgi to ER traffic 3 homolog;hARSA-I;hASNA-I;transmembrane domain recognition complex 40 kDa ATPase subunit;TRC40.
- Extra Details:
- ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors; where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state; facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently; the homodimer reverts towards the open dimer state; lowering its affinity for the membrane-bound receptor; and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.
- Gene Details:
- guided entry of tail-anchored proteins factor 3; ATPase
- Host:
- Human
- Molecular Weight:
- 54.7 kDa
- Protein Details:
- ATPase ASNA1
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
