Recombinant human TAR DNA-binding protein 43
Product Sizes
20ug
£398.00
OPCA01310-20UG
100ug
£550.00
OPCA01310-100UG
About this Product
- SKU:
- OPCA01310
- Additional Names:
- ALS10;TAR DNA-binding protein 43;TAR DNA-binding protein-43;TDP-43.
- Extra Details:
- DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis; apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
- Gene Details:
- TAR DNA binding protein
- Molecular Weight:
- 44.9 kDa
- Protein Details:
- TAR DNA-binding protein 43
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- Yeast
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
