Recombinant human MYL2
Product Sizes
20ug
£348.00
OPCA00857-20UG
100ug
£500.00
OPCA00857-100UG
1mg
£1822.00
OPCA00857-1MG
About this Product
- SKU:
- OPCA00857
- Additional Names:
- cardiac myosin light chain 2;cardiac ventricular myosin light chain 2;CMH10;MFM12;MLC2;MLC-2;MLC-2s/v;MLC-2v;Myosin light chain 2; slow skeletal/ventricular muscle isoform;myosin regulatory light chain 2; ventricular/cardiac muscle isoform;myosin; light chain 2; regulatory; cardiac; slow;myosin; light polypeptide 2; regulatory; cardiac; slow;regulatory light chain of myosin;RLC of myosin;slow cardiac myosin regulatory light chain 2;truncated myosin light chain 2;ventricular myosin light chain 2.
- Extra Details:
- Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation; plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity).
- Gene Details:
- myosin light chain 2
- Molecular Weight:
- 21.8 kDa
- Protein Details:
- Myosin regulatory light chain 2; ventricular/cardiac muscle isoform
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Purification:
- Affinity purified using IMAC
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
