Recombinant human Heat shock 70 kDa protein 6
Product Sizes
20ug
£348.00
OPCA00299-20UG
100ug
£500.00
OPCA00299-100UG
1mg
£1822.00
OPCA00299-1MG
About this Product
- SKU:
- OPCA00299
- Additional Names:
- epididymis secretory sperm binding protein;heat shock 70 kDa protein 6;heat shock 70 kDa protein B';heat shock 70kD protein 6 (HSP70B');heat shock 70kDa protein 6 (HSP70B');HSP70B'.
- Extra Details:
- Molecular chaperone implicated in a wide variety of cellular processes; including protection of the proteome from stress; folding and transport of newly synthesized polypeptides; activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system; ensuring the correct folding of proteins; the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding; ATP hydrolysis and ADP release; mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form; it has a low affinity for substrate proteins. However; upon hydrolysis of the ATP to ADP; it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange; which permits cycles of substrate binding and release (PubMed:26865365).
- Gene Details:
- heat shock protein family A (Hsp70) member 6
- Molecular Weight:
- 74.3 kDa
- Protein Details:
- Heat shock 70 kDa protein 6
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
