Recombinant human Prostaglandin G/H synthase 2
Product Sizes
20ug
£348.00
OPCA00192-20UG
100ug
£500.00
OPCA00192-100UG
1mg
£1822.00
OPCA00192-1MG
About this Product
- SKU:
- OPCA00192
- Additional Names:
- COX2;COX-2;cyclooxygenase 2;cyclooxygenase 2b;Cyclooxygenase-2;GRIPGHS;hCox-2;PGG/HS;PGH synthase 2;PGHS-2;PHS II;PHS-2;prostaglandin G/H synthase 2;prostaglandin H2 synthase 2;Prostaglandin-endoperoxide synthase 2;prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase).
- Extra Details:
- Converts arachidonate to prostaglandin H2 (PGH2); a committed step in prostanoid synthesis (PubMed:26859324; PubMed:27226593). Constitutively expressed in some tissues in physiological conditions; such as the endothelium; kidney and brain; and in pathological conditions; such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion; phenotypic changes; resistance to apoptosis and tumor angiogenesis. In cancer cells; PTGS2 is a key step in the production of prostaglandin E2 (PGE2); which plays important roles in modulating motility; proliferation and resistance to apoptosis.
- Gene Details:
- prostaglandin-endoperoxide synthase 2
- Molecular Weight:
- 70.9 kDa
- Protein Details:
- Prostaglandin G/H synthase 2
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
