Recombinant Mouse Integrin alpha-L
Product Sizes
20ug
£463.00
OPCA00139-20UG
100ug
£652.00
OPCA00139-100UG
1mg
£2446.00
OPCA00139-1MG
About this Product
- SKU:
- OPCA00139
- Additional Names:
- (p180);alpha L integrin;Cd11;CD11 antigen-like family member A;Cd11a;integrin alpha-L;leukocyte adhesion glycoprotein LFA-1 alpha chain;leukocyte function-associated molecule 1 alpha chain;LFA;LFA-1;LFA-1A;Ly-1;Ly-15;Ly-2;Ly-21;lymphocyte antigen 15;lymphocyte function associated antigen 1; alpha polypeptide.
- Extra Details:
- Integrin ITGAL/ITGB2 is a receptor for ICAM1; ICAM2; ICAM3 and ICAM4 (PubMed:2051027). Integrin ITGAL/ITGB2 is a receptor for F11R (By similarity). Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL (PubMed:29100055). Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction; cytotoxic T-cell mediated killing; and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:16234355; PubMed:24158516). Required for generation of common lymphoid progenitor cells in bone marrow; indicating the role in lymphopoiesis (PubMed:25108025). Integrin ITGAL/ITGB2 in association with ICAM3; contributes to apoptotic neutrophil phagocytosis by macrophages.
- Gene Details:
- integrin alpha L
- Molecular Weight:
- 23.7 kDa
- Protein Details:
- Integrin alpha-L
- Purity:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Source:
- E.coli
- Storage Conditions:
- -20Â[o]C or -80Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:html_datasheet.php
