MAPK8IP1 ELISA Kit
Product Sizes
96 Wells
£588.00
OKWB00352-96WELLS
About this Product
- SKU:
- OKWB00352
- Additional Names:
- C-Jun-amino-terminal kinase-interacting protein 1;IB-1;islet-brain-1;Jip-1;JIP1;JIP-1-related protein;JNK MAP kinase scaffold protein 1;JNK-interacting protein 1;JRP;Mapk8ip;mitogen activated protein kinase 8 interacting protein;Mitogen-activated protein kinase 8-interacting protein 1.
- Extra Details:
- The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and thus inhibiting the JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Directly; or indirectly; regulates GLUT2 gene expression and beta-cell function. Appears to have a role in cell signaling in mature and developing nerve terminals. May function as a regulator of vesicle transport; through interactions with the JNK-signaling components and motor proteins. Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response (By similarity).
- Gene Details:
- mitogen-activated protein kinase 8 interacting protein 1
- Protein Details:
- C-Jun-amino-terminal kinase-interacting protein 1
- Sensitivity:
- 0.938 ng/mL
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store as indicated in product manual.
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
- Manufacturer's Data Sheet:html_datasheet.php
