Dengue Virus IgM µ-capture ELISA Kit
Product Sizes
96 Wells
£452.00
OKNA00132-96WELLS
About this Product
- SKU:
- OKNA00132
- Additional Names:
- DENV
- Extra Details:
- Dengue fever; also known as breakbone fever; is an infectious tropical disease caused by the dengue virus and transmitted by mosquitoes. Dengue fever virus (DENV) is a virus of the family Flaviviridae; genus Flavivirus and contains a single-stranded RNA genome with positive polarity. There are four serotypes of the virus; which are referred to as DENV-1; DENV-2; DENV-3 and DENV-4. The geographical distribution is around the equator; particularly Latin America; Central Africa; India; Southeast Asia; Western Pacific and South of the USA. Dengue viruses are transmitted to humans through the bites of infective female yellow fever mosquitoes (Stegomyia aegypti; formerly Aedes aegypti). The mosquitoes generally acquire the virus while feeding on the blood of an infected person. After virus incubation for eight to ten days; an infected mosquito is capable; during probing and blood feeding; of transmitting the virus for the rest of its life. Yellow fever mosquitoes are well adapted to living in close proximity to humans; and to feeding off people rather than other vertebrates. They prefer to lay their eggs in artificial water containers; such as flower vases; uncovered barrels; buckets and discarded tires. The incubation period ranges from 3-14 days; but most often it is 4-7 days. Typically; people infected with dengue virus are asymptomatic or only have symptoms of a common cold. The characteristic symptoms of dengue are sudden-onset fever (up to 40 C) with intense headache (especially behind the eyes); and muscle and joint pain. In combination with a skin rash this symptoms are known as the „dengue triad“. This usually lasts 3-7 days. In some patients the disease proceeds to a critical phase. Dengue Hemorrhagic Fever (DHF) or Dengue Shock Syndrome (DSS) occur in less than 5 % of all cases of dengue. About 1-5 % of severe cases are fatal. In individual epidemics the case-fatality rate may reach up to 15 %. Infection with one serotype is believed to produce lifelong immunity to that serotype but only short term protection against the others. Secondary infection with a different serotype may result in severe clinical manifestations. There is no vaccination available.
- Protein Details:
- Dengue Virus u-capture IgM
- Sensitivity:
- Sensitivity is determined as the probability of the assay indicating a positive score in samples with the specific analyte present: > 98%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store as indicated in product manual.
- Supplier:
- Aviva Systems Biology
- Type:
- Assay Kits: ELISAs
